SP1 Protein (His tag)
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- Target See all SP1 Proteins
- SP1 (Sp1 Transcription Factor (SP1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SP1 protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SP1 / TSFP1 (full length, N-term HIS tag, transcript variant 1) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SP1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris,8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SP1 (Sp1 Transcription Factor (SP1))
- Alternative Name
- Sp1,tsfp1 (SP1 Products)
- Synonyms
- fc18h09 Protein, zgc:85950 Protein, wu:fc18h09 Protein, SP1 Protein, 1110003E12Rik Protein, AA450830 Protein, AI845540 Protein, Sp1-1 Protein, sp1 transcription factor Protein, Sp1 transcription factor Protein, Sp1 transcription factor L homeolog Protein, trans-acting transcription factor 1 Protein, sp1 Protein, SP1 Protein, Sp1 Protein, sp1.L Protein
- Background
- The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 80.5 kDa
- NCBI Accession
- NP_612482
- Pathways
- Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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