Spastin Protein (SPAST) (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all Spastin (SPAST) Proteins
- Spastin (SPAST)
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This Spastin protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Spastin / SPAST (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPAST Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- Spastin (SPAST)
- Alternative Name
- Spastin,spast (SPAST Products)
- Synonyms
- CG5977 Protein, D-spastin Protein, Dmel\\CG5977 Protein, Dspastin Protein, Spas Protein, zgc:85952 Protein, SPAST Protein, spg4 Protein, LOC100224472 Protein, ADPSP Protein, FSP2 Protein, SPG4 Protein, Spg4 Protein, mKIAA1083 Protein, spastin Protein, spastin S homeolog Protein, spas Protein, spast Protein, SPAST Protein, Spast Protein, spast.S Protein
- Background
- This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
- Molecular Weight
- 67 kDa
- NCBI Accession
- NP_055761
- Pathways
- Microtubule Dynamics, M Phase, Regulation of Cell Size
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