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Spastin Protein (SPAST) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

SPAST Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2732512
  • Target See all Spastin (SPAST) Proteins
    Spastin (SPAST)
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 1
    Origin
    • 4
    • 2
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Spastin protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Spastin / SPAST (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product SPAST Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Spastin (SPAST)
    Alternative Name
    Spastin,spast (SPAST Products)
    Synonyms
    CG5977 Protein, D-spastin Protein, Dmel\\CG5977 Protein, Dspastin Protein, Spas Protein, zgc:85952 Protein, SPAST Protein, spg4 Protein, LOC100224472 Protein, ADPSP Protein, FSP2 Protein, SPG4 Protein, Spg4 Protein, mKIAA1083 Protein, spastin Protein, spastin S homeolog Protein, spas Protein, spast Protein, SPAST Protein, Spast Protein, spast.S Protein
    Background
    This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The encoded ATPase may be involved in the assembly or function of nuclear protein complexes. Two transcript variants encoding distinct isoforms have been identified for this gene. Other alternative splice variants have been described but their full length sequences have not been determined. Mutations associated with this gene cause the most frequent form of autosomal dominant spastic paraplegia 4.
    Molecular Weight
    67 kDa
    NCBI Accession
    NP_055761
    Pathways
    Microtubule Dynamics, M Phase, Regulation of Cell Size
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