SPOP-B Protein (Transcript Variant 6) (Myc-DYKDDDDK Tag)
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- Target See all SPOP-B Proteins
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 6
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPOP-B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human SPOP (transcript variant 6) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPOP-B Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPOP-B (Speckle-Type POZ Protein (SPOP-B))
- Alternative Name
- Spop (SPOP-B Products)
- Synonyms
- BTBD32 Protein, TEF2 Protein, AI315626 Protein, Pcif1 Protein, zgc:64140 Protein, spop Protein, tef2 Protein, speckle type BTB/POZ protein Protein, speckle-type POZ protein Protein, speckle type POZ protein S homeolog Protein, SPOP Protein, Spop Protein, spop Protein, spop.S Protein
- Background
- This gene encodes a protein that may modulate the transcriptional repression activities of death-associated protein 6 (DAXX), which interacts with histone deacetylase, core histones, and other histone-associated proteins. In mouse, the encoded protein binds to the putative leucine zipper domain of macroH2A1.2, a variant H2A histone that is enriched on inactivated X chromosomes. The BTB/POZ domain of this protein has been shown in other proteins to mediate transcriptional repression and to interact with components of histone deacetylase co-repressor complexes. Alternative splicing of this gene results in multiple transcript variants encoding the same protein.
- Molecular Weight
- 42 kDa
- NCBI Accession
- NP_001007230
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