SPRY2 Protein (Myc-DYKDDDDK Tag)
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- Target See all SPRY2 Proteins
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This SPRY2 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Sprouty homolog 2 / SPRY2 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product SPRY2 Protein
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Sprouty Homolog 2 (SPRY2) (AA 1-315) protein (GST tag)
SPRY2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Sprouty Homolog 2 (SPRY2) (AA 1-315) protein (Strep Tag)Crystallography grade SPRY2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Sprouty Homolog 2 (SPRY2) (AA 1-315) protein (Strep Tag)Crystallography grade SPRY2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Sprouty Homolog 2 (SPRY2) proteinSPRY2 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Sprouty Homolog 2 (SPRY2) proteinSPRY2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- SPRY2 (Sprouty Homolog 2 (SPRY2))
- Alternative Name
- Sprouty Homolog 2,spry2 (SPRY2 Products)
- Synonyms
- wu:fk66h11 Protein, wu:fk93e11 Protein, zgc:110440 Protein, hspry2 Protein, xspry2 Protein, sprouty2 Protein, Xsprouty2 Protein, sprouty-2 Protein, Xtsprouty2 Protein, hSPRY2 Protein, sprouty RTK signaling antagonist 2 Protein, sprouty RTK signaling antagonist 2 S homeolog Protein, sprouty homolog 2 (Drosophila) Protein, spry2 Protein, SPRY2 Protein, spry2.S Protein, Spry2 Protein
- Background
- This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.
- Molecular Weight
- 34.5 kDa
- NCBI Accession
- NP_005833
- Pathways
- EGFR Signaling Pathway, Sensory Perception of Sound, EGFR Downregulation
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