TRIM21 Protein (Myc-DYKDDDDK Tag)
-
- Target See all TRIM21 Proteins
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
- Protein Type
- Recombinant
-
Origin
- Human
-
Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TRIM21 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
-
- Recombinant human SS-A / Ro52 / TRIM21 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TRIM21 Protein
-
-
- Application Notes
-
Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
-
The tag is located at the C-terminal.
- Restrictions
- For Research Use only
-
- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
-
- Target
- TRIM21 (Tripartite Motif Containing 21 (TRIM21))
- Alternative Name
- Ss-A,ro52,trim21 (TRIM21 Products)
- Synonyms
- RNF81 Protein, RO52 Protein, SSA Protein, SSA1 Protein, Ro52 Protein, Ssa1 Protein, tripartite motif containing 21 Protein, tripartite motif-containing 21 Protein, TRIM21 Protein, Trim21 Protein
- Background
- This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined.
- Molecular Weight
- 54 kDa
- NCBI Accession
- NP_003132
-