TFE3 Protein (Myc-DYKDDDDK Tag)
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- Target See all TFE3 Proteins
- TFE3 (Transcription Factor E3 (TFE3))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TFE3 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human TFE3 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TFE3 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TFE3 (Transcription Factor E3 (TFE3))
- Alternative Name
- Tfe3 (TFE3 Products)
- Synonyms
- RCCP2 Protein, RCCX1 Protein, TFEA Protein, bHLHe33 Protein, F830016E06Rik Protein, Tcfe3 Protein, Tfe-3 Protein, RGD1559642 Protein, cb873 Protein, zgc:109815 Protein, transcription factor binding to IGHM enhancer 3 Protein, transcription factor E3 Protein, transcription factor binding to IGHM enhancer 3 S homeolog Protein, transcription factor binding to IGHM enhancer 3a Protein, TFE3 Protein, Tfe3 Protein, tfe3.S Protein, tfe3a Protein
- Background
- Transcription factor that specifically recognizes and binds E-box sequences (5'-CANNTG-3'). Efficient DNA-binding requires dimerization with itself or with another MiT/TFE family member such as TFEB or MITF. In association with TFEB, activates the expression of CD40L in T-cells, thereby playing a role in T-cell-dependent antibody responses in activated CD4(+) T-cells and thymus-dependent humoral immunity. Specifically recognizes the MUE3 box, a subset of E-boxes, present in the immunoglobulin enhancer. It also binds very well to a USF/MLTF site. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 61.3 kDa
- NCBI Accession
- NP_006512
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