TXNDC5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734681

Product Details

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TXNDC5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human TXNDC5 / TLP46 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))

Alternative Name: Txndc5,tlp46 (TXNDC5 Products)

Synonyms: ENDOPDI Protein, ERP46 Protein, HCC-2 Protein, PDIA15 Protein, STRF8 Protein, UNQ364 Protein, wu:fb20a07 Protein, wu:fb55b10 Protein, zgc:66265 Protein, AL022641 Protein, ERp46 Protein, PC-TRP Protein, PDIL5-1 Protein, Txndc5 Protein, erp46 Protein, TXNDC5 Protein, MUTED Protein, endopdi Protein, unq364 Protein, thioredoxin domain containing 5 Protein, protein disulfide isomerase Protein, thioredoxin domain containing 5 L homeolog Protein, biogenesis of lysosomal organelles complex 1 subunit 5 Protein, TXNDC5 Protein, txndc5 Protein, Txndc5 Protein, PDIL5-1 Protein, txndc5.L Protein, BLOC1S5 Protein, CC1G_08236 Protein

Background: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.

Molecular Weight: 44.4 kDa

NCBI Accession: NP_110437

Pathways: Cell RedoxHomeostasis