TXNDC5 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all TXNDC5 Proteins
- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This TXNDC5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Thioredoxin domain containing 5 (TXNDC5), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product TXNDC5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- TXNDC5 (Thioredoxin Domain Containing 5 (Endoplasmic Reticulum) (TXNDC5))
- Alternative Name
- Thioredoxin Domain Containing 5 (Txndc5) (TXNDC5 Products)
- Synonyms
- ENDOPDI Protein, ERP46 Protein, HCC-2 Protein, PDIA15 Protein, STRF8 Protein, UNQ364 Protein, wu:fb20a07 Protein, wu:fb55b10 Protein, zgc:66265 Protein, AL022641 Protein, ERp46 Protein, PC-TRP Protein, PDIL5-1 Protein, Txndc5 Protein, erp46 Protein, TXNDC5 Protein, MUTED Protein, endopdi Protein, unq364 Protein, thioredoxin domain containing 5 Protein, protein disulfide isomerase Protein, thioredoxin domain containing 5 L homeolog Protein, biogenesis of lysosomal organelles complex 1 subunit 5 Protein, TXNDC5 Protein, txndc5 Protein, Txndc5 Protein, PDIL5-1 Protein, txndc5.L Protein, BLOC1S5 Protein, CC1G_08236 Protein
- Background
- This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal endoplasmic reticulum (ER)-signal sequence, three catalytically active thioredoxin domains and a C-terminal ER-retention sequence. Its expression is induced by hypoxia and its role may be to protect hypoxic cells from apoptosis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring upstream BLOC1S5 gene.
- Molecular Weight
- 43.5 kDa
- NCBI Accession
- NP_071368
- Pathways
- Cell RedoxHomeostasis
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