ITK Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734725

Product Details

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This ITK protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Tyrosine-protein kinase ITK/TSK protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: ITK (IL2-Inducible T-Cell Kinase (ITK))

Alternative Name: Tyrosine-Protein Kinase Itk/tsk (ITK Products)

Synonyms: Emt Protein, Tcsk Protein, Tsk Protein, EMT Protein, LPFS1 Protein, LYK Protein, PSCTK2 Protein, IL2 inducible T cell kinase Protein, IL2 inducible T-cell kinase Protein, IL2-inducible T-cell kinase Protein, Itk Protein, ITK Protein

Background: This gene encodes an intracellular tyrosine kinase expressed in T-cells. The protein contains both SH2 and SH3 domains which are often found in intracellular kinases. It is thought to play a role in T-cell proliferation and differentiation.

Molecular Weight: 71.7 kDa

NCBI Accession: NP_005537

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway