UGT2A1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734970

Product Details

Target: UGT2A1 (UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UGT2A1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UDP glucuronosyltransferase 2 family, polypeptide A1 (UGT2A1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UGT2A1 (UDP Glucuronosyltransferase 2 Family, Polypeptide A1, Complex Locus (UGT2A1))

Alternative Name: Udp Glucuronosyltransferase 2 Family, Polypeptide a1 (Ugt2a1) (UGT2A1 Products)

Synonyms: Ugt2a1p Protein, UDP glucuronosyltransferase 2 family, polypeptide A1 Protein, UDP glucuronosyltransferase family 2 member A1 complex locus Protein, ugt2a1 Protein, Ugt2a1 Protein, UGT2A1 Protein

Background: The protein encoded by this gene belongs to the UDP-glycosyltransferase family, members of which catalyze biotransformation reactions in which lipophilic substrates are conjugated with glucuronic acid to increase water solubility and enhance excretion. They are of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms.

Molecular Weight: 59.7 kDa

NCBI Accession: NP_006789

Pathways: Steroid Hormone Biosynthesis