UGT1A3 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2734990

Product Details

Target: UGT1A3 (UDP Glucuronosyltransferase 1 Family, Polypeptide A3 (UGT1A3))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This UGT1A3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human UGT1A3 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: UGT1A3 (UDP Glucuronosyltransferase 1 Family, Polypeptide A3 (UGT1A3))

Alternative Name: Ugt1a3 (UGT1A3 Products)

Synonyms: DKFZP469K1510 Protein, UDPGT Protein, UDPGT 1-3 Protein, UGT-1C Protein, UGT1-03 Protein, UGT1.3 Protein, UGT1C Protein, Ugt1 Protein, Ugt1a4 Protein, UDP glucuronosyltransferase 1 family, polypeptide A3 Protein, UDP-glucuronosyltransferase 1-10 Protein, UDP glucuronosyltransferase family 1 member A3 Protein, UDP glycosyltransferase 1 family, polypeptide A3 Protein, UGT1A3 Protein, LOC100511841 Protein, Ugt1a3 Protein

Background: This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. Substrates of this enzyme include estrone, 2-hydroxyestrone, and metabolites of benzo alpha-pyrene.

Molecular Weight: 57.3 kDa

NCBI Accession: NP_061966