VPS4A Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735431

Product Details

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This VPS4A protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human VPS4A protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))

Alternative Name: Vps4a (VPS4A Products)

Synonyms: vsp4 Protein, SKD1 Protein, SKD1A Protein, SKD2 Protein, VPS4 Protein, VPS4-1 Protein, zgc:153907 Protein, 4930589C15Rik Protein, AI325971 Protein, AW553189 Protein, vacuolar protein sorting 4 homolog A Protein, vacuolar sorting protein 4 Protein, vacuolar protein sorting 4 homolog A L homeolog Protein, vacuolar protein sorting 4a homolog A (S. cerevisiae) Protein, vacuolar protein sorting 4A Protein, VPS4A Protein, TP03_0351 Protein, vps4a Protein, vps4a.L Protein, Vps4a Protein

Background: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16 the gene for the other resides on chromosome 18.

Molecular Weight: 48.7 kDa

NCBI Accession: NP_037377

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events