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VPS4A Protein (His tag)

VPS4A Origin: Human Host: HEK-293 Cells Recombinant The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
Catalog No. ABIN7491269
  • Target See all VPS4A Proteins
    VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
    Protein Type
    Recombinant
    Origin
    Human
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This VPS4A protein is labelled with His tag.
    Purpose
    Recombinant Human VPS4 Protein with C-terminal 6xHis tag
    Specificity
    VPS4 (Met1-Ser437) 6xHis tag
    Characteristics
    Extracellular Domain Protein
    Purity
    The purity of the protein is greater than 85 % as determined by SDS-PAGE and Coomassie blue staining.
    Top Product
    Discover our top product VPS4A Protein
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization.
    Storage
    -20 °C,-80 °C
    Storage Comment
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    Expiry Date
    12 months
  • Target
    VPS4A (Vacuolar Protein Sorting-Associated Protein 4A (VPS4A))
    Alternative Name
    VPS4 (VPS4A Products)
    Synonyms
    vsp4 Protein, SKD1 Protein, SKD1A Protein, SKD2 Protein, VPS4 Protein, VPS4-1 Protein, zgc:153907 Protein, 4930589C15Rik Protein, AI325971 Protein, AW553189 Protein, vacuolar protein sorting 4 homolog A Protein, vacuolar sorting protein 4 Protein, vacuolar protein sorting 4 homolog A L homeolog Protein, vacuolar protein sorting 4a homolog A (S. cerevisiae) Protein, vacuolar protein sorting 4A Protein, VPS4A Protein, TP03_0351 Protein, vps4a Protein, vps4a.L Protein, Vps4a Protein
    Background
    CIMDAG, SKD1, SKD1A, SKD2, VPS4A, VPS4-1
    Description: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. The mouse Skd1 (suppressor of K transport defect 1) has been shown to be really an yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 16, the gene for the other resides on chromosome 18. [provided by RefSeq, Jul 2008]
    Molecular Weight
    predicted molecular mass of 49.7 kDa after removal of the signal peptide. The apparent molecular mass of VPS4-His is 55-70 kDa due to glycosylation.
    UniProt
    Q9UN37
    Pathways
    Microtubule Dynamics, CXCR4-mediated Signaling Events
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