VPS4B Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2735432

Product Details

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This VPS4B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human VPS4B protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: VPS4B (vps4b) (Vacuolar Protein Sorting 4 Homolog B (vps4b))

Alternative Name: Vps4b (vps4b Products)

Synonyms: zgc:63682 Protein, vps4a Protein, SKD1 Protein, SKD1B Protein, VPS4-2 Protein, 8030489C12Rik Protein, Skd1 Protein, vacuolar protein sorting 4 homolog B Protein, vacuolar protein sorting 4 homolog B S homeolog Protein, vacuolar protein sorting 4b homolog B (S. cerevisiae) Protein, vacuolar protein sorting 4 homolog B (S. cerevisiae) Protein, vacuolar protein sorting 4B Protein, Vps4b Protein, vps4b.S Protein, vps4b Protein, VPS4B Protein

Background: The protein encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18 the gene for the other resides on chromosome 16.

Molecular Weight: 49.1 kDa

NCBI Accession: NP_004860

Pathways: Microtubule Dynamics, CXCR4-mediated Signaling Events