XCL1 Protein
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- Target See all XCL1 Proteins
- XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Antibody Production (AbP), Standard (STD), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human XCL1 / Lymphotactin protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- Endotoxin level is <0.1 ng/μg of protein (<1EU/μg).
- Biological Activity Comment
- Determined by its ability to chemoattract human T cells using a concentration of 10.0-100.0 ng/ml.
- Top Product
- Discover our top product XCL1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM phosphate buffer,100 mM NaCl, pH 7.2
- Handling Advice
- Resuspend the protein in the desired concentration in proper buffer
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- XCL1 (Chemokine (C Motif) Ligand 1 (XCL1))
- Alternative Name
- Xcl1,lymphotactin (XCL1 Products)
- Synonyms
- ATAC Protein, LPTN Protein, LTN Protein, SCM-1 Protein, SCM-1a Protein, SCM1 Protein, SCM1A Protein, SCYC1 Protein, AI661682 Protein, Lptn Protein, Scyc1 Protein, Ltn Protein, XCL1 Protein, XCL2 Protein, X-C motif chemokine ligand 1 Protein, chemokine (C motif) ligand 1 Protein, cytokine SCM-1 beta Protein, lymphotactin Protein, XCL1 Protein, Xcl1 Protein, LOC490356 Protein, LOC100714756 Protein, LOC100349255 Protein
- Background
- This antimicrobial gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1.
- Molecular Weight
- 10 kDa
- NCBI Accession
- NP_002986
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation
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