CCDC50 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all CCDC50 Proteins
- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
- Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This CCDC50 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Ymer (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- CCDC50 (Coiled-Coil Domain Containing 50 (CCDC50))
- Alternative Name
- Ymer (CCDC50 Products)
- Synonyms
- ymer Protein, C3orf6 Protein, DFNA44 Protein, YMER Protein, 2610529H08Rik Protein, 5730448P06Rik Protein, AW048328 Protein, AW546090 Protein, D16Bwg1543e Protein, C3orf6h Protein, c3orf6 Protein, coiled-coil domain containing 50 Protein, coiled-coil domain containing 50 L homeolog Protein, CCDC50 Protein, ccdc50.L Protein, ccdc50 Protein, Ccdc50 Protein
- Background
- This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
- Molecular Weight
- 35.6 kDa
- NCBI Accession
- NP_777568
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