Trefoil Factor 2 Protein (TFF2) (AA 24-129) (His tag)

Catalog No. ABIN4370732

Product Details

Target: Trefoil Factor 2 (TFF2)

Protein Type: Recombinant

Protein Characteristics: AA 24-129

Origin: Human

Source: Human Cells

Purification tag / Conjugate: This Trefoil Factor 2 protein is labelled with His tag.

Purpose: Recombinant Human Trefoil Factor 2/TFF2 (C-6His)

Sequence: EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHYVDHH HHHH

Characteristics: Recombinant Human Trefoil Factor 2/TFF2 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Gln24-Tyr129) of Human TFF2 fused with a polyhistidine tag at the C-terminus.

Purity: > 95 % as determined by reducing SDS-PAGE.

Sterility: 0.2 μm filtered

Endotoxin Level: Less than 0.1 ng/μg (1 IEU/μg) as determined by LAL test

Application Details

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: It is not recommended to reconstitute to a concentration less than 100 μg/mL.
Dissolve the lyophilized protein in ddH2O.
Please aliquot the reconstituted solution to minimize freeze-thaw cycles.

Buffer: Lyophilized from a 0.2 μm filtered solution of 20 mM PB,150 mM NaCl, pH 7.2.

Handling Advice: Always centrifuge tubes before opening. Do not mix by vortex or pipetting.

Storage: 4 °C/-20 °C/-80 °C

Storage Comment: Lyophilized protein should be stored at < -20°C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7°C for 2-7 days.
Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Expiry Date: 3 months

Target Details

Target: Trefoil Factor 2 (TFF2)

Alternative Name: TFF2 (TFF2 Products)

Synonyms: TFF2 Protein, SML1 Protein, SP Protein, PSP Protein, p4 Protein, p4-a Protein, sml1 Protein, xP4 Protein, xp4.1 Protein, mSP Protein, trefoil factor 2 Protein, trefoil factor 2 S homeolog Protein, trefoil factor 2 (spasmolytic protein 1) Protein, TFF2 Protein, Tff2 Protein, tff2.S Protein

Sub Type: Fusionprotein

Background: Trefoil Factor 2 (TFF2) is a member of the trefoil family and contains two P-type (trefoil) domains. Members of this family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. TFF2 is a secreted protein and specifically expressed in the stomach. TFF2 inhibits gastrointestinal motility and gastric acid secretion. TFF2 could function as a structural component of gastric mucus, possibly by stabilizing glycoproteins in the mucus gel through interactions with carbohydrate side chains.
Alternative Names: Trefoil Factor 2, Spasmolysin, Spasmolytic Polypeptide, SP, TFF2, SML1

Molecular Weight: 13 kDa

UniProt: Q03403