DCP2 Protein (AA 1-385, Isoform 2) (His tag)
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- Target See all DCP2 Proteins
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
- Protein Type
- Recombinant
- Protein Characteristics
- Isoform 2, AA 1-385
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This DCP2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- METKRVEIPG SVLDDLCSRF ILHIPSEERD NAIRVCFQIE LAHWFYLDFY MQNTPGLPQC GIRDFAKAVF SHCPFLLPQG EDVEKVLDEW KEYKMGVPTY GAIILDETLE NVLLVQGYLA KSGWGFPKGK VNKEEAPHDC AAREVFEETG FDIKDYICKD DYIELRINDQ LARLYIIPGI PKDTKFNPKT RREIRNIEWF SIEKLPCHRN DMTPKSKLGL APNKFFMAIP FIRPLRDWLS RRFGDSSDSD NGFSSTGSTP AKPTVEKLSR TKFRHSQQLF PDGSPGDQWV KHRQPLQQKP YNNHSEMSDL LKGKKCEKKL HPRKLQDNFE TDAVYDLPSS SEDQLLEHAE GQPVACNGHC KFPFSSRAFL SFKFDHNAIM KILDL
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product DCP2 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- DCP2 (DCP2 Decapping Enzyme Homolog (DCP2))
- Alternative Name
- DCP2 (DCP2 Products)
- Synonyms
- DDBDRAFT_0185453 Protein, DDBDRAFT_0252811 Protein, DDB_0185453 Protein, DDB_0252811 Protein, 2410015D23Rik Protein, 5730537H01Rik Protein, AL118268 Protein, NUDT20 Protein, RGD1562909 Protein, mRNA-decapping enzyme 2 Protein, hypothetical protein Protein, decapping mRNA 2 Protein, CpipJ_CPIJ019463 Protein, PTRG_05936 Protein, dcp2 Protein, MCYG_05106 Protein, MGYG_07617 Protein, PGTG_03310 Protein, Tsp_04018 Protein, DCP2 Protein, Dcp2 Protein
- Background
- Decapping metalloenzyme that catalyzes the cleavage of the cap structure on mRNAs. Roves the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Plays a role in replication-dependent histone mRNA degradation. Has higher activity towards mRNAs that lack a poly(A) tail. Has no activity towards a cap structure lacking an RNA moiety
- Molecular Weight
- 48.5 kDa
- UniProt
- Q8IU60
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