GZMB Protein (GST tag,His tag)
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- Target See all GZMB Proteins
- GZMB (Granzyme B (GZMB))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GZMB protein is labelled with GST tag,His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Purified recombinant protein of Human granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB), full length, with N-terminal GST and C-terminal His tag, expressed in E. coli, 50 μg (full length, N-term GST tag, C-term His tag) protein expressed in E.coli.
- Produced with end-sequenced ORF clone
- Purification
- Purified
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product GZMB Protein
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Granzyme B (GZMB) (AA 21-247) protein (GST tag)
GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 148-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) (AA 1-247) protein (GST tag)GZMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Granzyme B (GZMB) protein (His tag)GZMB Origin: Mouse Host: Human Cells Recombinant > 85 % as determined by SDS-PAGE
Granzyme B (GZMB) (AA 21-247) protein (His tag)Crystallography grade GZMB Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Granzyme B (GZMB) (AA 21-247) protein (His tag)Crystallography grade GZMB Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal,N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- GZMB (Granzyme B (GZMB))
- Alternative Name
- granzyme B (GZMB Products)
- Synonyms
- CCPI Protein, CGL-1 Protein, CGL1 Protein, CSP-B Protein, CSPB Protein, CTLA1 Protein, CTSGL1 Protein, HLP Protein, SECT Protein, granzyme B Protein, GZMB Protein
- Background
- This gene encodes a member of the granzyme subfamily of proteins, part of the peptidase S1 family of serine proteases. The encoded preproprotein is secreted by natural killer (NK) cells and cytotoxic T lymphocytes (CTLs) and proteolytically processed to generate the active protease, which induces target cell apoptosis. This protein also processes cytokines and degrades extracellular matrix proteins, and these roles are implicated in chronic inflammation and wound healing. Expression of this gene may be elevated in human patients with cardiac fibrosis.
- Molecular Weight
- 51.5 kDa
- NCBI Accession
- NP_004122
- Pathways
- Apoptosis, Caspase Cascade in Apoptosis
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