TLR5 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN5505661

Product Details

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This TLR5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Purified recombinant protein of Homo sapiens toll-like receptor 5 (TLR5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purification: Purified

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: TLR5 (Toll-Like Receptor 5 (TLR5))

Alternative Name: TLR5 (TLR5 Products)

Synonyms: SLEB1 Protein, TIL3 Protein, TLR-5 Protein, sleb1 Protein, til3 Protein, tlr-5 Protein, tlr5 Protein, toll like receptor 5 Protein, toll-like receptor 5 Protein, toll like receptor 5 L homeolog Protein, toll-like receptor 5b Protein, TLR5 Protein, Tlr5 Protein, tlr5.L Protein, tlr-5 Protein, tlr5b Protein

Background: This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.[provided by RefSeq, Dec 2009]

Molecular Weight: 95.7 kDa

NCBI Accession: NP_003259

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades