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CD28 Protein (CD28) (partial) (His tag)

This Recombinant CD28 protein is expressed in HEK-293 Cells.
Catalog No. ABIN5608228

Quick Overview for CD28 Protein (CD28) (partial) (His tag) (ABIN5608228)

Target

See all CD28 Proteins
CD28

Protein Type

Recombinant

Origin

  • 21
  • 12
  • 9
  • 7
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
Mouse

Source

  • 19
  • 5
  • 4
  • 4
  • 3
  • 3
  • 2
  • 1
  • 1
HEK-293 Cells

Application

Western Blotting (WB)

Purity

>85 % as determined by SDS-PAGE.
  • Protein Characteristics

    partial

    Purification tag / Conjugate

    This CD28 protein is labelled with His tag.

    Sequence

    Asn 20 - Lys 149

    Endotoxin Level

    Endotoxin level is less than 1.0 EU per ug by the LAL method.
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  • Application Notes

    This recombinant protein can be used for WB.

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Buffer

    PBS, pH 7.4

    Handling Advice

    Avoid repeated freeze-thaw cycles.

    Storage

    -20 °C,-80 °C

    Storage Comment

    Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C.
  • Target

    CD28

    Alternative Name

    CD28

    Background

    T-cell-specific surface glycoprotein CD28 is also known as TP44, is a single-pass type I membrane protein which contains one Ig-like V-type (immunoglobulin-like) domain. is one of the molecules expressed on T cells that provide co-stimulatory signals, which are required for T cell activation. CD28 is the receptor for CD80 (B7.1) and CD86 (B7.2). When activated by Toll-like receptor ligands, the CD80 expression is upregulated in antigen presenting cells (APCs). The CD86 expression on antigen presenting cells is constitutive. CD28 is the only B7 receptor constitutively expressed on naive T cells.

    Molecular Weight

    17 kDa

    Gene ID

    12487

    NCBI Accession

    NP_031668

    UniProt

    P31041

    Pathways

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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