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Iba1 Protein (AA 2-147, partial) (His-SUMO Tag)

IBA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
Catalog No. ABIN5709019
  • Target See all Iba1 (IBA1) Proteins
    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
    Protein Type
    Recombinant
    Protein Characteristics
    partial, AA 2-147
    Origin
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 10
    • 5
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This Iba1 protein is labelled with His-SUMO Tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    SQTRDLQGGK AFGLLKAQQE ERLDEINKQF LDDPKYSSDE DLPSKLEGFK EKYMEFDLNG NGDIDIMSLK RMLEKLGVPK THLELKKLIG EVSSGSGETF SYPDFLRMML GKRSAILKMI LMYEEKAREK EKPTGPPAKK AISELP
    Purification
    SDS-PAGE
    Purity
    > 90 %
    Top Product
    Discover our top product IBA1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.1-2 mg/mL
    Buffer
    20 mM Tris-HCl based buffer, pH 8.0
    Storage
    -80 °C,4 °C,-20 °C
    Storage Comment
    Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
  • Target
    Iba1 (IBA1) (Ionized Calcium-binding Adapter Molecule 1 (IBA1))
    Alternative Name
    AIF1 (IBA1 Products)
    Synonyms
    AIF-1 Protein, IBA1 Protein, IRT-1 Protein, IRT1 Protein, AI607846 Protein, D17H6S50E Protein, G1 Protein, Iba1 Protein, Bart1 Protein, iba1 Protein, mrf-1 Protein, fa04b11 Protein, wu:fa04b11 Protein, AIF Protein, AIF1 Protein, aif1 Protein, allograft inflammatory factor 1 Protein, AIF1 Protein, Aif1 Protein, aif1 Protein
    Background
    Actin-binding protein that enhances mbrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the proliferation of vascular smooth muscle cells and of T-lymphocytes. Enhances lymphocyte migration. Plays a role in vascular inflammation.
    Molecular Weight
    32.6 kDa
    UniProt
    P55008
    Pathways
    Smooth Muscle Cell Migration
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