BMPR1A Protein (AA 177-532) (His-SUMO Tag)

Catalog No. ABIN5709147

Product Details

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Protein Type: Recombinant

Protein Characteristics: AA 177-532

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This BMPR1A protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: KHYCKSISSR RRYNRDLEQD EAFIPVGESL KDLIDQSQSS GSGSGLPLLV QRTIAKQIQM VRQVGKGRYG EVWMGKWRGE KVAVKVFFTT EEASWFRETE IYQTVLMRHE NILGFIAADI KGTGSWTQLY LITDYHENGS LYDFLKCATL DTRALLKLAY SAACGLCHLH TEIYGTQGKP AIAHRDLKSK NILIKKNGSC CIADLGLAVK FNSDTNEVDV PLNTRVGTKR YMAPEVLDES LNKNHFQPYI MADIYSFGLI IWEMARRCIT GGIVEEYQLP YYNMVPSDPS YEDMREVVCV KRLRPIVSNR WNSDECLRAV LKLMSECWAH NPASRLTALR IKKTLAKMVE SQDVKI

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: BMPR1A (Bone Morphogenetic Protein Receptor 1A (BMPR1A))

Alternative Name: BMR1A (BMPR1A Products)

Synonyms: 10q23del Protein, ACVRLK3 Protein, ALK3 Protein, CD292 Protein, SKR5 Protein, 1110037I22Rik Protein, AU045487 Protein, BMPR-IA Protein, Bmpr Protein, BMPR-1 Protein, BRK-1 Protein, BMPR1A Protein, acvrlk3 Protein, alk-3 Protein, alk3 Protein, cd292 Protein, skr5 Protein, BR1a Protein, alk3tr Protein, bmpr1a Protein, zgc:136731 Protein, wu:fe05b06 Protein, wu:fe06e10 Protein, zgc:92227 Protein, bone morphogenetic protein receptor type 1A Protein, bone morphogenetic protein receptor, type 1A Protein, bone morphogenetic protein receptor type 1A S homeolog Protein, bone morphogenetic protein receptor, type IAa Protein, bone morphogenetic protein receptor, type IAb Protein, BMPR1A Protein, Bmpr1a Protein, bmpr1a Protein, bmpr1a.S Protein, bmpr1aa Protein, bmpr1ab Protein

Background: On ligand binding, forms a receptor complex consisting of two type II and two type I transmbrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4. Positively regulates chondrocyte differentiation through GDF5 interaction .

Molecular Weight: 56.57 kDa

UniProt: P36894

Pathways: Stem Cell Maintenance