CD59 Protein (CD59) (AA 26-102) (GST tag)
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- Target See all CD59 Proteins
- CD59
- Protein Type
- Recombinant
- Protein Characteristics
- AA 26-102
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CD59 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- LQCYNCPNPT ADCKTAVNCS SDFDACLITK AGLQVYNKCW KFEHCNFNDV TTRLRENELT YYCCKKDLCN FNEQLEN
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product CD59 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- CD59
- Alternative Name
- CD59 (CD59 Products)
- Synonyms
- 16.3A5 Protein, 1F5 Protein, EJ16 Protein, EJ30 Protein, EL32 Protein, G344 Protein, HRF-20 Protein, HRF20 Protein, MAC-IP Protein, MACIF Protein, MEM43 Protein, MIC11 Protein, MIN1 Protein, MIN2 Protein, MIN3 Protein, MIRL Protein, MSK21 Protein, p18-20 Protein, Cd59a Protein, Cd59b Protein, MACIP Protein, CD59 molecule (CD59 blood group) Protein, CD59 molecule Protein, CD59 Protein, Cd59 Protein
- Background
- Potent inhibitor of the complent mbrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complents of the assbling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase.The soluble form from urine retains its specific complent binding activity, but exhibits greatly reduced ability to inhibit MAC assbly on cell mbranes.
- Molecular Weight
- 36.4 kDa
- UniProt
- P13987
- Pathways
- Complement System
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