COL4A1 Protein (AA 1445-1669) (His-SUMO Tag)
COL4A1
Origin: Human
Host: Escherichia coli (E. coli)
Recombinant
> 90 %
SDS
1 image
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- Target See all COL4A1 Proteins
- COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1445-1669
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This COL4A1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GFLVTRHSQT IDDPQCPSGT KILYHGYSLL YVQGNERAHG QDLGTAGSCL RKFSTMPFLF CNINNVCNFA SRNDYSYWLS TPEPMPMSMA PITGENIRPF ISRCAVCEAP AMVMAVHSQT IQIPPCPSGW SSLWIGYSFV MHTSAGAEGS GQALASPGSC LEEFRSAPFI ECHGRGTCNY YANAYSFWLA TIERSEMFKK PTPSTLKAGE LRTHVSRCQV CMRRT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product COL4A1 Protein
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Collagen, Type IV, alpha 1 (COL4A1) (AA 30-167), (partial) protein (GST tag)
COL4A1 Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % SDS, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- COL4A1 (Collagen, Type IV, alpha 1 (COL4A1))
- Alternative Name
- CO4A1 (COL4A1 Products)
- Synonyms
- col4a1 Protein, wu:fc02g11 Protein, HANAC Protein, ICH Protein, POREN1 Protein, arresten Protein, Bru Protein, Col4a-1 Protein, Del(8)44H Protein, Raw Protein, Svc Protein, collagen, type IV, alpha 5 (Alport syndrome) Protein, collagen type IV alpha 1 chain Protein, collagen, type IV, alpha 1 Protein, col4a5 Protein, COL4A1 Protein, Col4a1 Protein
- Background
- Type IV collagen is the major structural component of glomerular basent mbranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin.
- Molecular Weight
- 40.9 kDa
- UniProt
- P02462
- Pathways
- Skeletal Muscle Fiber Development, Growth Factor Binding
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