EIF4EBP3 Protein (AA 1-100, full length) (His-SUMO Tag)
-
- Target See all EIF4EBP3 Proteins
- EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-100, full length
-
Origin
- Human
-
Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This EIF4EBP3 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSTSTSCPIP GGRDQLPDCY STTPGGTLYA TTPGGTRIIY DRKFLLECKN SPIARTPPCC LPQIPGVTTP PTAPLSKLEE LKEQETEEEI PDDAQFEMDI
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product EIF4EBP3 Protein
-
-
- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
-
- Target
- EIF4EBP3 (Eukaryotic Translation Initiation Factor 4E Binding Protein 3 (EIF4EBP3))
- Alternative Name
- 4EBP3 (EIF4EBP3 Products)
- Synonyms
- zgc:103720 Protein, 4E-BP3 Protein, 4EBP3 Protein, 4e-bp3 Protein, eukaryotic translation initiation factor 4E binding protein 3 Protein, eif4ebp3 Protein, Eif4ebp3 Protein, EIF4EBP3 Protein
- Background
- Repressor of translation initiation that regulates EIF4E activity by preventing its assbly into the eIF4F complex: hypophosphorylated form competes with EIF4G1/EIF4G3 and strongly binds to EIF4E, leading to repress translation. In contrast, hyperphosphorylated form dissociates from EIF4E, allowing interaction between EIF4G1/EIF4G3 and EIF4E, leading to initiation of translation.
- Molecular Weight
- 26.87 kDa
- UniProt
- O60516
-