GDF9 Protein (AA 320-454) (GST tag)
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- Target See all GDF9 Proteins
- GDF9 (Growth Differentiation Factor 9 (GDF9))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 320-454
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This GDF9 protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- GQETVSSELK KPLGPASFNL SEYFRQFLLP QNECELHDFR LSFSQLKWDN WIVAPHRYNP RYCKGDCPRA VGHRYGSPVH TMVQNIIYEK LDSSVPRPSC VPAKYSPLSV LTIEPDGSIA YKEYEDMIAT KCTCR
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product GDF9 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- GDF9 (Growth Differentiation Factor 9 (GDF9))
- Alternative Name
- GDF9 (GDF9 Products)
- Synonyms
- GDF-9 Protein, zgc:123030 Protein, Gdf-9 Protein, growth differentiation factor 9 Protein, GDF9 Protein, gdf9 Protein, Gdf9 Protein
- Background
- Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
- Molecular Weight
- 42.9 kDa
- UniProt
- O60383
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