KCNJ10 Protein (AA 165-379, Cytoplasmic Domain, Cytosolic) (His-SUMO Tag)
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- Target See all KCNJ10 Proteins
- KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
- Protein Type
- Recombinant
- Protein Characteristics
- Cytosolic, AA 165-379, Cytoplasmic Domain
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This KCNJ10 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- FLAKIARPKK RAETIRFSQH AVVASHNGKP CLMIRVANMR KSLLIGCQVT GKLLQTHQTK EGENIRLNQV NVTFQVDTAS DSPFLILPLT FYHVVDETSP LKDLPLRSGE GDFELVLILS GTVESTSATC QVRTSYLPEE ILWGYEFTPA ISLSASGKYI ADFSLFDQVV KVASPSGLRD STVRYGDPEK LKLEESLREQ AEKEGSALSV RISNV
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product KCNJ10 Protein
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Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) (AA 276-379) protein (GST tag)
KCNJ10 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) (AA 165-379) protein (His tag)Crystallography grade KCNJ10 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) (AA 1-379) protein (Strep Tag)Crystallography grade KCNJ10 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10) (AA 1-379) protein (Strep Tag)Crystallography grade KCNJ10 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- KCNJ10 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 10 (KCNJ10))
- Alternative Name
- KCJ10 (KCNJ10 Products)
- Synonyms
- kir1.2 Protein, kir4.1 Protein, birk-10 Protein, MGC145926 Protein, BIR10 Protein, BIRK-1 Protein, Kir1.2 Protein, Kir4.1 Protein, BIRK-10 Protein, KCNJ13-PEN Protein, KIR1.2 Protein, KIR4.1 Protein, SESAME Protein, potassium channel, inwardly rectifying subfamily J, member 10 L homeolog Protein, potassium voltage-gated channel subfamily J member 10 Protein, potassium channel, inwardly rectifying subfamily J, member 10 Protein, potassium inwardly-rectifying channel, subfamily J, member 10 Protein, kcnj10.L Protein, KCNJ10 Protein, kcnj10 Protein, Kcnj10 Protein
- Background
- May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium, as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium .
- Molecular Weight
- 39.8 kDa
- UniProt
- P78508
- Pathways
- Dicarboxylic Acid Transport, Regulation of long-term Neuronal Synaptic Plasticity
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