SAMHD1 Protein (AA 395-626) (His tag)
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- Target See all SAMHD1 Proteins
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 395-626
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Origin
- Mouse
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SAMHD1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- DIMITDAFLK ADPYVEITGT AGKKFRISTA IDDMEAFTKL TDNIFLEVLH STDPQLSEAQ SILRNIECRN LYKYLGETQP KREKIRKEEY ERLPQEVAKA KPEKAPDVEL KAEDFIVDVI NVDYGMEDKN PIDRVHFYCK SNSKQAVRIN KEQVSQLLPE KFAEQLIRVY CKKKDGKSLD AAGKHFVQWC ALRDFTKPQD GDIIAPLITP LKWNNKTSSC LQEVSKVKTC LK
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product SAMHD1 Protein
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SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) protein (GST tag)
SAMHD1 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
SAM Domain and HD Domain 1 (SAMHD1) (AA 1-626) protein (Strep Tag)Crystallography grade SAMHD1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
SAM Domain and HD Domain 1 (SAMHD1) (AA 1-627) protein (His tag)Crystallography grade SAMHD1 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB, Crys
SAM Domain and HD Domain 1 (SAMHD1) protein (Myc-DYKDDDDK Tag)SAMHD1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- SAMHD1 (SAM Domain and HD Domain 1 (SAMHD1))
- Alternative Name
- SAMH1 (SAMHD1 Products)
- Synonyms
- CHBL2 Protein, DCIP Protein, HDDC1 Protein, MOP-5 Protein, SBBI88 Protein, si:dkeyp-44b8.8 Protein, E330031J07Rik Protein, Mg11 Protein, SAM and HD domain containing deoxynucleoside triphosphate triphosphohydrolase 1 Protein, SAM domain and HD domain 1 Protein, SAM domain and HD domain, 1 Protein, SAMHD1 Protein, samhd1 Protein, Samhd1 Protein
- Background
- Host restriction nuclease that blocks early-stage virus replication in dendritic and other myeloid cells. Likewise, suppresses LINE-1 retrotransposon activity. May function by reducing the cellular dNTP levels to levels too low for retroviral reverse transcription to occur. May play a role in mediating proinflammatory responses to TNF-alpha signaling .
- Molecular Weight
- 30.7 kDa
- UniProt
- Q60710
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