PDZK1 Protein (Myc-DYKDDDDK Tag)
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- Target See all PDZK1 Proteins
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDZK1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDZD1 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDZK1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDZK1 (PDZ Domain Containing 1 (PDZK1))
- Alternative Name
- Pdzd1 (PDZK1 Products)
- Synonyms
- xpdzk1 Protein, PDZK1 Protein, CAP70 Protein, CLAMP Protein, NHERF-3 Protein, NHERF3 Protein, PDZD1 Protein, 1700023D20Rik Protein, 2610507N21Rik Protein, 4921513F16Rik Protein, AI267131 Protein, AI314638 Protein, AL022680 Protein, D3Ertd537e Protein, Pdzd1 Protein, mPDZK1 Protein, Clamp Protein, PDZ domain containing 1 Protein, PDZ domain containing 1 L homeolog Protein, PDZK1 Protein, pdzk1.L Protein, pdzk1 Protein, Pdzk1 Protein
- Background
- This gene encodes a PDZ domain-containing scaffolding protein. PDZ domain-containing molecules bind to and mediate the subcellular localization of target proteins. The encoded protein mediates the localization of cell surface proteins and plays a critical role in cholesterol metabolism by regulating the HDL receptor, scavenger receptor class B type 1. Single nucleotide polymorphisms in this gene may be associated with metabolic syndrome, and overexpression of this gene may play a role in drug resistance of multiple myeloma. Pseudogenes of this gene are located on the long arm of chromosome 1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
- Molecular Weight
- 56.9 kDa
- NCBI Accession
- NP_002605
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