PTPMT1 Protein (AA 28-201) (His-SUMO Tag)
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- Target See all PTPMT1 Proteins
- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-201
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PTPMT1 protein is labelled with His-SUMO Tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- KVPGRAHRDW YHRIDPTVLL GALPLRSLTR QLVQDENVRG VITMNEEYET RFLCNSSQEW KRLGVEQLRL STVDMTGIPT LDNLQKGVQF ALKYQSLGQC VYVHCKAGRS RSATMVAAYL IQVHKWSPEE AVRAIAKIRS YIHIRPGQLD VLKEFHKQIT ARATKDGTFV ISKT
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product PTPMT1 Protein
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Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1) (AA 28-201) protein (His tag)
PTPMT1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1) (AA 1-201) protein (GST tag)PTPMT1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1) (AA 32-193) protein (His tag)Crystallography grade PTPMT1 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- PTPMT1 (Protein Tyrosine Phosphatase, Mitochondrial 1 (PTPMT1))
- Alternative Name
- PTPM1 (PTPMT1 Products)
- Synonyms
- im:7137979 Protein, zgc:158719 Protein, DUSP23 Protein, MOSP Protein, PLIP Protein, 1110001D10Rik Protein, 2810004N20Rik Protein, Plip Protein, protein tyrosine phosphatase, mitochondrial 1 Protein, PTPMT1 Protein, ptpmt1 Protein, Ptpmt1 Protein
- Background
- Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG). PGP is an essential intermediate in the biosynthetic pathway of cardiolipin, a mitochondrial-specific phospholipid regulating the mbrane integrity and activities of the organelle. Has also been shown to display phosphatase activity toward phosphoprotein substrates, specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells .
- Molecular Weight
- 35.9 kDa
- UniProt
- Q8WUK0
- Pathways
- Inositol Metabolic Process
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