HIST1H2BN Protein (AA 2-126) (His-SUMO Tag)

Catalog No. ABIN5711721

Product Details

Target: HIST1H2BN (Histone H2B Type 1-N (HIST1H2BN))

Protein Type: Recombinant

Protein Characteristics: AA 2-126

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This HIST1H2BN protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: PEPSKSAPAP KKGSKKAVTK AQKKDGKKRK RSRKESYSVY VYKVLKQVHP DTGISSKAMG IMNSFVNDIF ERIAGEASRL AHYNKRSTIT SREIQTAVRL LLPGELAKHA VSEGTKAVTK YTSSK

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: HIST1H2BN (Histone H2B Type 1-N (HIST1H2BN))

Alternative Name: H2B1N (HIST1H2BN Products)

Synonyms: H2B/d Protein, H2BFD Protein, HIST1H2BM Protein, HIST1H2BN Protein, histone cluster 1 H2B family member n Protein, histone cluster 1, H2bn Protein, HIST1H2BN Protein, Hist1h2bn Protein, HIST1H2BB Protein

Background: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a tplate. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome rodeling.

Molecular Weight: 29.78 kDa

UniProt: Q99877