NLE1 Protein (AA 2-485) (His-SUMO Tag)

Catalog No. ABIN5711937

Product Details

Target: NLE1 (Notchless Homolog 1 (NLE1))

Protein Type: Recombinant

Protein Characteristics: AA 2-485

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NLE1 protein is labelled with His-SUMO Tag.

Application: SDS-PAGE (SDS)

Sequence: AAAVADEAVA RDVQRLLVQF QDEGGQLLGS PFDVPVDITP DRLQLVCNAL LAQEDPLPLA FFVHDAEIVS SLGKTLESQA VETEKVLDII YQPQAIFRVR AVTRCTSSLE GHSEAVISVA FSPTGKYLAS GSGDTTVRFW DLSTETPHFT CKGHRHWVLS ISWSPDGKKL ASGCKNGQIL LWDPSTGKQV GRTLAGHSKW ITGLSWEPLH ANPECRYVAS SSKDGSVRIW DTTAGRCERI LTGHTQSVTC LRWGGDGLLY SASQDRTIKV WRAHDGVLCR TLQGHGHWVN TMALSTDYAL RTGAFEPAEA SVNPQDLQGS LQELKERALS RYNLVRGQGP ERLVSGSDDF TLFLWSPAED KKPLTRMTGH QALINQVLFS PDSRIVASAS FDKSIKLWDG RTGKYLASLR GHVAAVYQIA WSADSRLLVS GSSDSTLKVW DVKAQKLAMD LPGHADEVYA VDWSPDGQRV ASGGKDKCLR IWRR

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: NLE1 (Notchless Homolog 1 (NLE1))

Alternative Name: NLE1 (NLE1 Products)

Synonyms: Nle Protein, AL022765 Protein, BC018399 Protein, l11Jus1 Protein, l11Jus4 Protein, RGD1308301 Protein, notchless homolog 1 Protein, notchless homolog 1 (Drosophila) Protein, NLE1 Protein, Nle1 Protein

Background: Plays a role in regulating Notch activity. Plays a role in regulating the expression of CDKN1A and several mbers of the Wnt pathway, probably via its effects on Notch activity. Required during bryogenesis for inner mass cell survival .

Molecular Weight: 69.1 kDa

UniProt: Q9NVX2