EIF4A2 Protein (AA 1-407, full length) (GST tag)

Catalog No. ABIN5712053

Product Details

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Protein Type: Recombinant

Protein Characteristics: full length, AA 1-407

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This EIF4A2 protein is labelled with GST tag.

Application: SDS-PAGE (SDS)

Sequence: MSGGSADYNR EHGGPEGMDP DGVIESNWNE IVDNFDDMNL KESLLRGIYA YGFEKPSAIQ QRAIIPCIKG YDVIAQAQSG TGKTATFAIS ILQQLEIEFK ETQALVLAPT RELAQQIQKV ILALGDYMGA TCHACIGGTN VRNEMQKLQA EAPHIVVGTP GRVFDMLNRR YLSPKWIKMF VLDEADEMLS RGFKDQIYEI FQKLNTSIQV VLLSATMPTD VLEVTKKFMR DPIRILVKKE ELTLEGIKQF YINVEREEWK LDTLCDLYET LTITQAVIFL NTRRKVDWLT EKMHARDFTV SALHGDMDQK ERDVIMREFR SGSSRVLITT DLLARGIDVQ QVSLVINYDL PTNRENYIHR IGRGGRFGRK GVAINFVTEE DKRILRDIET FYNTTVEEMP MNVADLI

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: EIF4A2 (Eukaryotic Translation Initiation Factor 4A2 (EIF4A2))

Alternative Name: IF4A2 (EIF4A2 Products)

Synonyms: BM-010 Protein, DDX2B Protein, EIF4A Protein, EIF4F Protein, eIF-4A-II Protein, eIF4A-II Protein, 4833432N07Rik Protein, Ddx2b Protein, Eif4 Protein, ddx2b Protein, eif4aii Protein, eif4f Protein, xeif4aii Protein, EIF4A2 Protein, EIF4AII Protein, wu:fd50g11 Protein, zgc:63783 Protein, eukaryotic translation initiation factor 4A2 Protein, eukaryotic translation initiation factor 4A2 L homeolog Protein, microRNA 1248 Protein, eukaryotic translation initiation factor 4A, isoform 2 Protein, Eif4a2 Protein, EIF4A2 Protein, eif4a2.L Protein, eif4a2 Protein, MIR1248 Protein

Background: ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

Molecular Weight: 73.8 kDa

UniProt: Q14240