HNRNPK Protein (AA 3-459, partial) (GST tag)
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- Target See all HNRNPK Proteins
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 3-459, partial
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This HNRNPK protein is labelled with GST tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- TEQPEETFPN TETNGEFGKR PAEDMEEEQA FKRSRNTDEM VELRILLQSK NAGAVIGKGG KNIKALRTDY NASVSVPDSS GPERILSISA DIETIGEILK KIIPTLEEGL QLPSPTATSQ LPLESDAVEC LNYQHYKGSD FDCELRLLIH QSLAGGIIGV KGAKIKELRE NTQTTIKLFQ ECCPHSTDRV VLIGGKPDRV VECIKIILDL ISESPIKGRA QPYDPNFYDE TYDYGGFTMM FDDRRGRPVG FPMRGRGGFD RMPPGRGGRP MPPSRRDYDD MSPRRGPPPP PPGRGGRGGS RARNLPLPPP PPPRGGDLMA YDRRGRPGDR YDGMVGFSAD ETWDSAIDTW SPSEWQMAYE PQGGSGYDYS YAGGRGSYGD LGGPIITTQV TIPKDLAGSI IGKGGQRIKQ IRHESGASIK IDEPLEGSED RIITITGTQD QIQNAQYLLQ NSVKQYADVE GF
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product HNRNPK Protein
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Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) protein (GST tag)
HNRNPK Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) protein (Strep Tag)Crystallography grade HNRNPK Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-463) protein (Strep Tag)Crystallography grade HNRNPK Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, ELISA, WB
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 3-459), (partial) protein (GST tag)HNRNPK Origin: Human Host: Escherichia coli (E. coli) Recombinant 90 % ELISA
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 1) (Active) protein (Myc-DYKDDDDK Tag)HNRNPK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD, Func, PI Active
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (AA 1-276) protein (His tag)HNRNPK Origin: Human Host: Escherichia coli (E. coli) Recombinant > 95 % by SDS - PAGE SDS
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)HNRNPK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)HNRNPK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- HNRNPK (Heterogeneous Nuclear Ribonucleoprotein K (HNRNPK))
- Alternative Name
- HNRPK (HNRNPK Products)
- Synonyms
- CSBP Protein, HNRPK Protein, TUNP Protein, Csbp Protein, Hnrpk Protein, hnrpk Protein, MGC75642 Protein, wu:fb37h02 Protein, wu:fi34c04 Protein, zgc:66162 Protein, KBBP Protein, NOVA Protein, heterogeneous nuclear ribonucleoprotein K Protein, heterogeneous nuclear ribonucleoprotein K S homeolog Protein, heterogeneous nuclear ribonucleoprotein k Protein, HNRNPK Protein, Hnrnpk Protein, hnrnpk.S Protein, hnrnpk Protein, LOC5565718 Protein, CpipJ_CPIJ000130 Protein, NGK_p0004 Protein
- Background
- One of the major pre-mRNA-binding proteins. Binds tenaciously to poly(C) sequences. Likely to play a role in the nuclear metabolism of hnRNAs, particularly for pre-mRNAs that contain cytidine-rich sequences. Can also bind poly(C) single-stranded DNA. Plays an important role in p53/TP53 response to DNA damage, acting at the level of both transcription activation and repression. When sumoylated, acts as a transcriptional coactivator of p53/TP53, playing a role in p21/CDKN1A and 14-3-3 sigma/SFN induction . As far as transcription repression is concerned, acts by interacting with long intergenic RNA p21 (lincRNA-p21), a non-coding RNA induced by p53/TP53. This interaction is necessary for the induction of apoptosis, but not cell cycle arrest.3 Publications
- Molecular Weight
- 78.1 kDa
- UniProt
- P61978
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