CXCL7 Protein (AA 59-125, partial) (GST tag)

Catalog No. ABIN5712648

Product Details

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Protein Type: Recombinant

Protein Characteristics: partial, AA 59-125

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CXCL7 protein is labelled with GST tag.

Application: SDS-PAGE (SDS)

Sequence: AELRCMCIKT TSGIHPKNIQ SLEVIGKGTH CNQVEVIATL KDGRKICLDP DAPRIKKIVQ KKLAGDE

Purification: SDS-PAGE

Purity: > 90 %

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.1-2 mg/mL

Buffer: 20 mM Tris-HCl based buffer, pH 8.0

Storage: -80 °C,4 °C,-20 °C

Storage Comment: Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.

Target Details

Target: CXCL7 (PPBP) (Pro-Platelet Basic Protein (Chemokine (C-X-C Motif) Ligand 7) (PPBP))

Alternative Name: CXCL7 (PPBP Products)

Synonyms: 2400003M24Rik Protein, AI854500 Protein, CTAP3 Protein, CTAPIII Protein, Cxcl7 Protein, LA-PF4 Protein, LDGF Protein, MDGF Protein, NAP-2 Protein, NAP-2-L1 Protein, Scyb7 Protein, TGB Protein, TGB1 Protein, THBGB1 Protein, b-TG1 Protein, beta-TG Protein, B-TG1 Protein, Beta-TG Protein, CTAP-III Protein, CXCL7 Protein, PBP Protein, SCYB7 Protein, TC1 Protein, TC2 Protein, THBGB Protein, Nap-2 Protein, CTAPIII/NAP-2 Protein, Platelet basic protein Protein, pro-platelet basic protein Protein, scyb7 Protein, Ppbp Protein, PPBP Protein

Background: LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are choattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chokine-induced neutrophil activation.

Molecular Weight: 34.7 kDa

UniProt: P02775