RPA4 Protein (AA 1-260, partial) (His tag)
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- Target See all RPA4 Proteins
- RPA4 (Replication Protein A4, 30kDa (RPA4))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-260, partial
- Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RPA4 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MSKSGFGSYG SISAADGASG GSDQLCERDA TPAIKTQRPK VRIQDVVPCN VNQLLSSTVF DPVFKVRGII VSQVSIVGVI RGAEKASNHI CYKIDDMTAK PIEARQWFGR EKVKQVTPLS VGVYVKVFGI LKCPTGTKSL EVLKIHVLED MNEFTVHILE TVNAHMMLDK ARRDTTVESV PVSPSEVNDA GDNDESHRNF IQDEVLRLIH ECPHQEGKSI HELRAQLCDL SVKAIKEAID YLTVEGHIYP TVDREHFKSA
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product RPA4 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- RPA4 (Replication Protein A4, 30kDa (RPA4))
- Alternative Name
- RFA4 (RPA4 Products)
- Synonyms
- HSU24186 Protein, replication protein A4 Protein, RPA4 Protein
- Background
- As part of the alternative replication protein A complex, aRPA, binds single-stranded DNA and probably plays a role in DNA repair. Compared to the RPA2-containing, canonical RPA complex, may not support chromosomal DNA replication and cell cycle progression through S-phase. The aRPA may not promote efficient priming by DNA polymerase alpha but could support DNA polymerase delta synthesis in the presence of PCNA and replication factor C (RFC), the dual incision/excision reaction of nucleotide excision repair and RAD51-dependent strand exchange.
- Molecular Weight
- 32.8 kDa
- UniProt
- Q13156
- Pathways
- Mitotic G1-G1/S Phases, DNA Replication
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