DIO2 Protein (AA 1-266, full length) (His tag)
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- Target See all DIO2 Proteins
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-266, full length
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Origin
- Rat
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Source
- Yeast
- Purification tag / Conjugate
- This DIO2 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGLLSVDLLI TLQILPVFFS NCLFLALYDS VILLKHVALL LSRSKSTRGE WRRMLTSEGL RCVWNSFLLD AYKQVKLGED APNSSVVHVS NPEAGNNCAS EKTADGAECH LLDFASAERP LVVNFGSATU PPFTRQLPAF RQLVEEFSSV ADFLLVYIDE AHPSDGWAVP GDSSMSFEVK KHRNQEDRCA AAHQLLERFS LPPQCQVVAD RMDNNANVAY GVAFERVCIV QRRKIAYLGG KGPFSYNLQE VRSWLEKNFS KRSILDMGLL SVDLLITLQI LPVFFSNCLF LALYDSVILL KHVALLLSRS KSTRGEWRRM LTSEGLRCVW NSFLLDAYKQ VKLGEDAPNS SVVHVSNPEA GNNCASEKTA DGAECHLLDF ASAERPLVVN FGSATUPPFT RQLPAFRQLV EEFSSVADFL LVYIDEAHPS DGWAVPGDSS MSFEVKKHRN QEDRCAAAHQ LLERFSLPPQ CQVVADRMDN NANVAYGVAF ERVCIVQRRK IAYLGGKGPF SYNLQEVRSW LEKNFSKRSI LD
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product DIO2 Protein
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Deiodinase, Iodothyronine, Type II (DIO2) (AA 166-265) protein (GST tag)
DIO2 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Deiodinase, Iodothyronine, Type II (DIO2) (AA 1-273) protein (Strep Tag)Crystallography grade DIO2 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Deiodinase, Iodothyronine, Type II (DIO2) (AA 1-266) protein (Strep Tag)Crystallography grade DIO2 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA
Deiodinase, Iodothyronine, Type II (DIO2) proteinDIO2 Origin: Rat Host: Escherichia coli (E. coli) Recombinant > 95 % SDS, WB, ELISA, IP
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
- Alternative Name
- IOD2 (DIO2 Products)
- Synonyms
- 5DII Protein, D2 Protein, DIOII Protein, SelY Protein, TXDI2 Protein, AI324267 Protein, Deio2 Protein, cb684 Protein, DIO2 Protein, dio2-A Protein, 5dii Protein, sely Protein, txdi2 Protein, iodothyronine deiodinase 2 Protein, deiodinase, iodothyronine, type II Protein, deiodinase, iodothyronine, type 2 L homeolog Protein, deiodinase, iodothyronine, type 2 Protein, type II iodothyronine deiodinase Protein, DIO2 Protein, Dio2 Protein, dio2 Protein, dio2.L Protein, LOC100861220 Protein
- Background
- Catalyzes the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). Essential for providing the brain with appropriate levels of T3 during the critical period of development.
- Molecular Weight
- 61.5 kDa
- UniProt
- P70551
- Pathways
- Hormone Transport, Hormone Activity
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