MLKL Protein (AA 1-471, full length) (His tag)
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- Target See all MLKL Proteins
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Protein Type
- Recombinant
- Protein Characteristics
- full length, AA 1-471
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Origin
- Human
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Source
- Yeast
- Purification tag / Conjugate
- This MLKL protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MENLKHIITL GQVIHKRCEE MKYCKKQCRR LGHRVLGLIK PLEMLQDQGK RSVPSEKLTT AMNRFKAALE EANGEIEKFS NRSNICRFLT ASQDKILFKD VNRKLSDVWK ELSLLLQVEQ RMPVSPISQG ASWAQEDQQD ADEDRRAFQM LRRDNEKIEA SLRRLEINMK EIKETLRQYL PPKCMQEIPQ EQIKEIKKEQ LSGSPWILLR ENEVSTLYKG EYHRAPVAIK VFKKLQAGSI AIVRQTFNKE IKTMKKFESP NILRIFGICI DETVTPPQFS IVMEYCELGT LRELLDREKD LTLGKRMVLV LGAARGLYRL HHSEAPELHG KIRSSNFLVT QGYQVKLAGF ELRKTQTSMS LGTTREKTDR VKSTAYLSPQ ELEDVFYQYD VKSEIYSFGI VLWEIATGDI PFQGCNSEKI RKLVAVKRQQ EPLGEDCPSE LREIIDECRA HDPSVRPSVD EILKKLSTFS K
- Purification
- SDS-PAGE
- Purity
- > 90 %
- Top Product
- Discover our top product MLKL Protein
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Mixed Lineage Kinase Domain-Like (MLKL) (AA 371-471) protein (GST tag)
MLKL Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) protein (GST tag)MLKL Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471) protein (His tag)MLKL Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Mixed Lineage Kinase Domain-Like (MLKL) (AA 1-471), (full length) protein (His-SUMO Tag)MLKL Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.1-2 mg/mL
- Buffer
- 20 mM Tris-HCl based buffer, pH 8.0
- Storage
- -80 °C,4 °C,-20 °C
- Storage Comment
- Store at -20°C, for extended storage, conserve at -20°C or -80°C. Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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- Target
- MLKL (Mixed Lineage Kinase Domain-Like (MLKL))
- Alternative Name
- MLKL (MLKL Products)
- Synonyms
- MLKL Protein, 9130019I15Rik Protein, mixed lineage kinase domain like pseudokinase Protein, mixed lineage kinase domain-like Protein, MLKL Protein, mlkl Protein, Mlkl Protein
- Background
- Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma mbrane and execution of programmed necrosis characterized by calcium influx and plasma mbrane damage. Does not have protein kinase activity.
- Molecular Weight
- 56.48 kDa
- UniProt
- Q8NB16
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