SIKE1 Protein (AA 1-207) (His tag)
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- Target See all SIKE1 Proteins
- SIKE1 (Suppressor of IKBKE 1 (SIKE1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-207
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SIKE1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMSCTIEK ILTDAKTLLE RLREHDAAAE SLVDQSAALH RRVAAMREAG TALPDQYQED ASDMKDMSKY KPHILLSQEN TQIRDLQQEN RELWISLEEH QDALELIMSK YRKQMLQLMV AKKAVDAEPV LKAHQSHSAE IESQIDRICE MGEVMRKAVQ VDDDQFCKIQ EKLAQLELEN KELRELLSIS SESLQARKEN SMDTASQAIK
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SIKE1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SIKE1 (Suppressor of IKBKE 1 (SIKE1))
- Alternative Name
- SIKE1 (SIKE1 Products)
- Synonyms
- SIKE Protein, 2810005O12Rik Protein, 5730470L24Rik Protein, AI450236 Protein, AI839862 Protein, Sike Protein, Sikeb Protein, RGD1311316 Protein, suppressor of IKBKE 1 Protein, SIKE1 Protein, Sike1 Protein
- Background
- SIKE interacts with IKK-epsilon and TBK1 and acts as a suppressor of TLR3 and virus-triggered interferon activation pathways. Recombinant human SIKE1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 26.1 kDa (230aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_079349
- UniProt
- Q9BRV8
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