CSDC2 Protein (AA 1-153) (His tag)

Catalog No. ABIN5852940

Product Details

Target: CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))

Protein Type: Recombinant

Protein Characteristics: AA 1-153

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This CSDC2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMTSESTS PPVVPPLHSP KSPVWPTFPF HREGSRVWER GGVPPRDLPS PLPTKRTRTY SATARASAGP VFKGVCKQFS RSQGHGFITP ENGSEDIFVH VSDIEGEYVP VEGDEVTYKM CPIPPKNQKF QAVEVVLTQL APHTPHETWS GQVVGS

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 0.1M NaCl

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: CSDC2 (Cold Shock Domain Containing C2, RNA Binding (CSDC2))

Alternative Name: CSDC2 (CSDC2 Products)

Synonyms: pippin Protein, csdc2 Protein, zgc:91826 Protein, PIPPIN Protein, dJ347H13.2 Protein, AI415250 Protein, AI481750 Protein, Pippin Protein, cold shock domain containing C2, RNA binding Protein, cold shock domain containing C2 Protein, cold shock domain containing C2, RNA binding a Protein, cold shock domain containing C2 L homeolog Protein, CSDC2 Protein, csdc2 Protein, csdc2a Protein, csdc2.L Protein, Csdc2 Protein

Background: CSDC2, as known as cold shock domain-containing protein C2, is RNA-binding factor which binds specifically to the very 3'-uTR ends of both histone H1 and H3.3 mRNAs, encompassing the polyadenylation signal. The cold shock domain containing proteins (CSDPs) are one group of the evolutionarily conserved nucleic acid-binding proteins widely distributed in bacteria, plants, animals, and involved in various cellular processes, including adaptation to low temperature, cellular growth, nutrient stress and stationary phase. It may play a central role in the negative regulation of histone variant synthesis in the developing brain. Recombinant human CSDC2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Molecular Weight: 19.2 kDa(176aa) confirmed by MALDI-TOF

NCBI Accession: NP_055275

UniProt: Q9Y534