C1D Protein (AA 1-141) (His tag)
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- Target See all C1D Proteins
- C1D (C1D Nuclear Receptor Corepressor (C1D))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-141
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This C1D protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMAGEEIN EDYPVEIHEY LSAFENSIGA VDEMLKTMMS VSRNELLQKL DPLEQAKVDL VSAYTLNSMF WVYLATQGVN PKEHPVKQEL ERIRVYMNRV KEITDKKKAG KLDRGAASRF VKNALWEPKS KNASKVANKG KSKS
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product C1D Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- C1D (C1D Nuclear Receptor Corepressor (C1D))
- Alternative Name
- C1D (C1D Products)
- Synonyms
- LRP1 Protein, SUN-CoR Protein, SUNCOR Protein, hC1D Protein, 1110036E10Rik Protein, AI875855 Protein, zgc:103509 Protein, RGD1560600 Protein, C1D nuclear receptor corepressor Protein, C1D nuclear receptor corepressor L homeolog Protein, C1D nuclear receptor co-repressor Protein, C1D Protein, c1d Protein, c1d.L Protein, C1d Protein
- Background
- Nuclear nucleic acid-binding protein C1D, also known as C1D, plays a role in the recruitment of the RNA exosome complex to pre-rRNA to mediate the 3'-5' end processing of the 5.8S rRNA, this function may include MPHOSPH6. This protein can activate PRKDC not only in the presence of linear DNA but also in the presence of supercoiled DNA. This protein can induce apoptosis in a p53/TP53 dependent manner. Recombinant human C1D protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 18.4kDa (164aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_775269
- UniProt
- Q13901
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