NDUFS6 Protein (AA 28-124) (His tag)
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- Target See all NDUFS6 Proteins
- NDUFS6 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6, 13kDa (NADH-Coenzyme Q Reductase) (NDUFS6))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 28-124
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This NDUFS6 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSFGVRVSP TGEKVTHTGQ VYDDKDYRRI RFVGRQKEVN ENFAIDLIAE QPVSEVETRV IACDGGGGAL GHPKVYINLD KETKTGTCGY CGLQFRQHHH
- Purity
- > 90 % by SDS - PAGE
- Top Product
- Discover our top product NDUFS6 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.15M NaCl, 30 % glycerol, 1 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- NDUFS6 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 6, 13kDa (NADH-Coenzyme Q Reductase) (NDUFS6))
- Alternative Name
- NDuFS6 (NDUFS6 Products)
- Synonyms
- BC059730 Protein, IP13 Protein, Ip13dis Protein, Ndub13 Protein, RATIp13dis Protein, CI-13kA Protein, CI-13kD-A Protein, CI13KDA Protein, NADH dehydrogenase (ubiquinone) Fe-S protein 6 Protein, NADH:ubiquinone oxidoreductase subunit S6 Protein, Ndufs6 Protein, NDUFS6 Protein
- Background
- NDuFS6 is a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit is one of seven subunits in the iron-sulfur protein fraction. Mutations cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders. Recombinant human NDuFS6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques
- Molecular Weight
- 13.2kDa (120aa), confirmed by MALDI-TOF
- NCBI Accession
- NP_004544
- UniProt
- O75380
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