SIVA1 Protein (AA 1-175) (His tag)
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- Target See all SIVA1 Proteins
- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-175
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This SIVA1 protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMPKRSCP FADVAPLQLK VRVSQRELSR GVCAERYSQE VFEKTKRLLF LGAQAYLDHV WDEGCAVVHL PESPKPGPTG APRAARGQML IGPDGRLIRS LGQASEADPS GVASIACSSC VRAVDGKAVC GQCERALCGQ CVRTCWGCGS VACTLCGLVD CSDMYEKVLC TSCAMFET
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product SIVA1 Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.5 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
- Alternative Name
- SIVA1 (SIVA1 Products)
- Synonyms
- CD27BP Protein, SIVA Protein, Siva-1 Protein, Siva-2 Protein, CD27bp Protein, Siva Protein, SIVA1 apoptosis inducing factor Protein, SIVA1, apoptosis-inducing factor Protein, SIVA1 Protein, Siva1 Protein
- Background
- Apoptosis regulatory protein Siva isoform 1, also known as SIVA1, is a death domain-containing proapoptotic protein identified as an intracellular ligand of CD27 and of the glucocorticoid-induced TNFR family-related gene, which are two members of the TNFR family expressed on lymphoid cells. SIVA1 expression is up-regulated in multiple pathological processes, little is known about the signaling pathway underlying the Siva-induced apoptosis. Recombinant human SIVA1 protein, fused to His-tag at N-terminus, was expressed in E.coli. (denatured)
- Molecular Weight
- 21.1 kDa (198aa)
- NCBI Accession
- NP_006418
- UniProt
- O15304
- Pathways
- Positive Regulation of Endopeptidase Activity
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