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SIVA1 Protein (AA 1-175) (His tag)

SIVA1 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % by SDS - PAGE SDS
Catalog No. ABIN5853282
  • Target See all SIVA1 Proteins
    SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
    Protein Type
    Recombinant
    Protein Characteristics
    AA 1-175
    Origin
    • 6
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 2
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This SIVA1 protein is labelled with His tag.
    Application
    SDS-PAGE (SDS)
    Sequence
    MGSSHHHHHH SSGLVPRGSH MGSMPKRSCP FADVAPLQLK VRVSQRELSR GVCAERYSQE VFEKTKRLLF LGAQAYLDHV WDEGCAVVHL PESPKPGPTG APRAARGQML IGPDGRLIRS LGQASEADPS GVASIACSSC VRAVDGKAVC GQCERALCGQ CVRTCWGCGS VACTLCGLVD CSDMYEKVLC TSCAMFET
    Purity
    > 85 % by SDS - PAGE
    Top Product
    Discover our top product SIVA1 Protein
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Comment

    Denatured

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.5 mg/mL
    Buffer
    Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol, 0.4M urea
    Storage
    4 °C,-20 °C,-80 °C
    Storage Comment
    Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
  • Target
    SIVA1 (SIVA1, Apoptosis-Inducing Factor (SIVA1))
    Alternative Name
    SIVA1 (SIVA1 Products)
    Synonyms
    CD27BP Protein, SIVA Protein, Siva-1 Protein, Siva-2 Protein, CD27bp Protein, Siva Protein, SIVA1 apoptosis inducing factor Protein, SIVA1, apoptosis-inducing factor Protein, SIVA1 Protein, Siva1 Protein
    Background
    Apoptosis regulatory protein Siva isoform 1, also known as SIVA1, is a death domain-containing proapoptotic protein identified as an intracellular ligand of CD27 and of the glucocorticoid-induced TNFR family-related gene, which are two members of the TNFR family expressed on lymphoid cells. SIVA1 expression is up-regulated in multiple pathological processes, little is known about the signaling pathway underlying the Siva-induced apoptosis. Recombinant human SIVA1 protein, fused to His-tag at N-terminus, was expressed in E.coli. (denatured)
    Molecular Weight
    21.1 kDa (198aa)
    NCBI Accession
    NP_006418
    UniProt
    O15304
    Pathways
    Positive Regulation of Endopeptidase Activity
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