QKI Protein (AA 1-341) (His tag)
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- Target See all QKI Proteins
- QKI (Protein Quaking (QKI))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-341
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This QKI protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMVGEMET KEKPKPTPDY LMQLMNDKKL MSSLPNFCGI FNHLERLLDE EISRVRKDMY NDTLNGSTEK RSAELPDAVG PIVQLQEKLY VPVKEYPDFN FVGRILGPRG LTAKQLEAET GCKIMVRGKG SMRDKKKEEQ NRGKPNWEHL NEDLHVLITV EDAQNRAEIK LKRAVEEVKK LLVPAAEGED SLKKMQLMEL AILNGTYRDA NIKSPALAFS LAATAQAAPR IITGPAPVLP PAALRTPTPA GPTIMPLIRQ IQTAVMPNGT PHPTAAIVPP GPEAGLIYTP YEYPYTLAPA TSILEYPIEP SGVLGAVATK VRRHDMRVHP YQRIVTADRA ATGN
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product QKI Protein
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Protein Quaking (QKI) (AA 1-341) protein (His tag)
QKI Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Protein Quaking (QKI) (AA 1-319) protein (GST tag)QKI Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Protein Quaking (QKI) (Transcript Variant 3) protein (Myc-DYKDDDDK Tag)QKI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Quaking (QKI) (Transcript Variant 4) protein (Myc-DYKDDDDK Tag)QKI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Quaking (QKI) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)QKI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Protein Quaking (QKI) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)QKI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 0.25 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing 0.2M NaCl, 50 % glycerol, 2 mM DTT
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- QKI (Protein Quaking (QKI))
- Alternative Name
- QKI (QKI Products)
- Synonyms
- Hqk Protein, QK Protein, QK1 Protein, QK3 Protein, hqkI Protein, 1110003F05Rik Protein, 1500005P18 Protein, QkI Protein, l(17)-1Wis Protein, l17Wis1 Protein, Qki Protein, CQKI Protein, QKI-5 Protein, PqkI Protein, BqkI Protein, qk Protein, qk1 Protein, quaking Protein, Xqua Protein, qki Protein, EQKI Protein, EqkI Protein, QKI, KH domain containing RNA binding Protein, quaking Protein, QKI, KH domain containing, RNA binding S homeolog Protein, QKI, KH domain containing, RNA binding L homeolog Protein, QKI Protein, Qk Protein, qki.S Protein, qki.L Protein, Qki Protein
- Background
- Protein quaking isoform HQK-5, also known as QKI, is an RNA-binding protein that regulates pre-mRNA splicing, export of mRNAs from the nucleus, protein translation, and mRNA stability. It is involved in myelinization and oligodendrocyte differentiation, and it may play a role in schizophrenia. Defects or deletions in the QKI are associated with astrocytic tumors and may be involved in the pathogenesis of schizophrenia. Recombinant human QKI protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
- Molecular Weight
- 40.1 kDa (364aa) confirmed by MALDI-TOF
- NCBI Accession
- NP_006766
- UniProt
- Q96PU8
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