RAD51 Homolog B Protein (Rad51B) (AA 1-350) (His tag)
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- Target See all RAD51 Homolog B (Rad51B) Proteins
- RAD51 Homolog B (Rad51B)
- Protein Type
- Recombinant
- Protein Characteristics
- AA 1-350
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This RAD51 Homolog B protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSMGSKKLK RVGLSQELCD RLSRHQILTC QDFLCLSPLE LMKVTGLSYR GVHELLCMVS RACAPKMQTA YGIKAQRSAD FSPAFLSTTL SALDEALHGG VACGSLTEIT GPPGCGKTQF CIMMSILATL PTNMGGLEGA VVYIDTESAF SAERLVEIAE SRFPRYFNTE EKLLLTSSKV HLYRELTCDE VLQRIESLEE EIISKGIKLV ILDSVASVVR KEFDAQLQGN LKERNKFLAR EASSLKYLAE EFSIPVILTN QITTHLSGAL ASQADLVSPA DDLSLSEGTS GSSCVIAALG NTWSHSVNTR LILQYLDSER RQILIAKSPL APFTSFVYTI KEEGLVLQAY GNS
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product Rad51B Protein
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1.0 mg/mL
- Buffer
- Liquid. In 20 mM Tris-HCl buffer ( pH 8.0) containing , 10 % glycerol, 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- RAD51 Homolog B (Rad51B)
- Alternative Name
- RAD51B (Rad51B Products)
- Synonyms
- R51H2 Protein, RAD51L1 Protein, REC2 Protein, AI553500 Protein, Rad51l1 Protein, mREC2 Protein, ATRAD51B Protein, T17D12.12 Protein, T17D12_12 Protein, RGD1560681 Protein, rad51l1 Protein, wu:fd07f04 Protein, zgc:56581 Protein, RAD51 paralog B Protein, DNA repair (Rad51) family protein Protein, Rad51 DNA recombinase 2 Protein, RAD51B Protein, Rad51b Protein, rad51b Protein
- Background
- RAD51B is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Recombinant human RAD51B protein, fused to His-tag at N-terminus, was expressed in E.coli .
- Molecular Weight
- 40.6kDa (373aa)
- NCBI Accession
- NP_002868
- UniProt
- O15315
- Pathways
- DNA Damage Repair
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