KLF6 Protein (AA 1-283) (His tag)

Catalog No. ABIN5853533

Product Details

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Protein Type: Recombinant

Protein Characteristics: AA 1-283

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This KLF6 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMDVLPMC SIFQELQIVH ETGYFSALPS LEEYWQQTCL ELERYLQSEP CYVSASEIKF DSQEDLWTKI ILAREKKEES ELKISSSPPE DTLISPSFCY NLETNSLNSD VSSESSDSSE ELSPTAKFTS DPIGEVLVSS GKLSSSVTST PPSSPELSRE PSQLWGCVPG ELPSPGKVRS GTSGKPGDKG NGDASPDGRR RVHRCHFNGC RKVYTKSSHL KAHQRTHTGE KPYRCSWEGC EWRFARSDEL TRHFRKHTGA KPFKCSHCDR CFSRSDHLAL HMKRHL

Purity: > 85 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. 20  mM Tris-HCl buffer (  pH 8.0) containing 10 % glycerol 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: KLF6 (Kruppel-Like Factor 6 (KLF6))

Alternative Name: KLF6 (KLF6 Products)

Synonyms: gbf Protein, zf9 Protein, bcd1 Protein, cba1 Protein, cpbp Protein, pac1 Protein, st12 Protein, copeb Protein, MGC53475 Protein, KLF6 Protein, MGC127307 Protein, BCD1 Protein, CBA1 Protein, COPEB Protein, CPBP Protein, GBF Protein, PAC1 Protein, ST12 Protein, ZF9 Protein, AI448727 Protein, C86813 Protein, Copeb Protein, FM2 Protein, FM6 Protein, Ierepo1 Protein, Ierepo3 Protein, R75280 Protein, Zf9 Protein, Aa1017 Protein, klf6 Protein, cb538 Protein, wu:fb76d04 Protein, wu:fb92h03 Protein, wu:fe26g06 Protein, wu:fk78f12 Protein, Kruppel-like factor 6 L homeolog Protein, Kruppel like factor 6 Protein, Krueppel-like factor 6 Protein, Kruppel-like factor 6 Protein, Kruppel-like factor 6 S homeolog Protein, Kruppel-like factor 6a Protein, klf6.L Protein, KLF6 Protein, LOC100196412 Protein, klf6 Protein, Klf6 Protein, klf6.S Protein, klf6a Protein

Background: KLF6, also known as Krueppel-like factor 6, is a nuclear protein that has three zinc fingers. The zinc fingers of this protein are responsible for the specific DNA binding with the guanine-rich core promoter elements. The central region might be involved in activation or posttranslational regulatory pathways, and the acidic N-terminal domain might play an important role in the process of transcriptional activation. It is capable of activating transcription approximately 4-fold either on homologous or heterologous promoters. Recombinant human KLF6 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: 34.3 kDa(306aa) confirmed by MALDI-TOF

NCBI Accession: NP_001291

UniProt: Q99612