CRHBP Protein (AA 22-322) (His tag)
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- Target See all CRHBP Proteins
- CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))
- Protein Type
- Recombinant
- Protein Characteristics
- AA 22-322
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This CRHBP protein is labelled with His tag.
- Application
- SDS-PAGE (SDS)
- Sequence
- MGSSHHHHHH SSGLVPRGSH MGSESRYLEL REAADYDPFL LFSANLKREL AGEQPYRRAL RCLDMLSLQG QFTFTADRPQ LHCAAFFISE PEEFITIHYD QVSIDCQGGD FLKVFDGWIL KGEKFPSSQD HPLPSAERYI DFCESGLSRR SIRSSQNVAM IFFRVHEPGN GFTLTIKTDP NLFPCNVISQ TPNGKFTLVV PHQHRNCSFS IIYPVVIKIS DLTLGHVNGL QLKKSSAGCE GIGDFVELLG GTGLDPSKMT PLADLCYPFH GPAQMKVGCD NTVVRMVSSG KHVNRVTFEY RQLEPYELEN PNGNSIGEFC LSGL
- Purity
- > 85 % by SDS - PAGE
- Top Product
- Discover our top product CRHBP Protein
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Corticotropin Releasing Hormone Binding Protein (CRHBP) (AA 1-322) protein (GST tag)
CRHBP Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Corticotropin Releasing Hormone Binding Protein (CRHBP) (AA 25-322) protein (His tag)Crystallography grade CRHBP Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Corticotropin Releasing Hormone Binding Protein (CRHBP) (AA 25-322) protein (His tag)Crystallography grade CRHBP Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Corticotropin Releasing Hormone Binding Protein (CRHBP) protein (Myc-DYKDDDDK Tag)CRHBP Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Comment
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Denatured
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 mg/mL
- Buffer
- Liquid. 20 mM Tris-HCl buffer ( pH 8.0) containing 10 % glycerol 0.4M urea
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
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- Target
- CRHBP (Corticotropin Releasing Hormone Binding Protein (CRHBP))
- Alternative Name
- CRHBP (CRHBP Products)
- Synonyms
- crh-BP Protein, GB14094 Protein, zgc:91905 Protein, CRHBP Protein, CRH-BP Protein, CRF-BP Protein, CRFBP Protein, Crfbp Protein, crhbp-A Protein, gene E Protein, corticotropin releasing hormone binding protein Protein, corticotropin releasing hormone binding protein S homeolog Protein, CRHBP Protein, crhbp Protein, crh-BP Protein, Crhbp Protein, crhbp.S Protein
- Background
- Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy. Recombinant human CRHBP protein, fused to His-tag at N-terminus, was expressed in E.coli.
- Molecular Weight
- 36.1 kDa(324aa)
- NCBI Accession
- NP_001873
- UniProt
- P24387
- Pathways
- Negative Regulation of Hormone Secretion
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