BHMT2 Protein (AA 1-363) (His tag)

Catalog No. ABIN7280670

Product Details

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Protein Type: Recombinant

Protein Characteristics: AA 1-363

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This BHMT2 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAPAGRP GAKKGILERL ESGEVVIGDG SFLITLEKRG YVKAGLWTPE AVIEHPDAVR QLHMEFLRAG SNVMQTFTFS ASEDNMESKW EDVNAAACDL AREVAGKGDA LVAGGICQTS IYKYQKDEAR IKKLFRQQLE VFAWKNVDFL IAEYFEHVEE AVWAVEVLKE SDRPVAVTMC IGPEGDMHDI TPGECAVRLV KAGASIVGVN CRFGPDTSLK TMELMKEGLE WAGLKAHLMV QPLGFHAPDC GKEGFVDLPE YPFGLESRVA TRWDIQKYAR EAYNLGVRYI GGCCGFEPYH IRAIAEELAP ERGFLPPASE KHGSWGSGLD MHTKPWIRAR ARREYWENLL PASGRPFCPS LSKPDF

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Denatured

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 0.4M urea, 10 % glycerol

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: BHMT2 (Betaine--Homocysteine S-Methyltransferase 2 (BHMT2))

Alternative Name: BHMT2 (BHMT2 Products)

Synonyms: C81077 Protein, D13Ucla2 Protein, BHMT2 Protein, DKFZp469M1332 Protein, bhmt-2 Protein, betaine--homocysteine S-methyltransferase 2 Protein, betaine-homocysteine methyltransferase 2 Protein, betaine-homocysteine S-methyltransferase 2 Protein, S-methylmethionine--homocysteine S-methyltransferase BHMT2 Protein, BHMT2 Protein, Bhmt2 Protein, LOC100073266 Protein

Background: BHMT2 is involved in the regulation of homocysteine metabolism. Homocysteine is a sulfur-containing amino acid that plays a crucial role in methylation reactions. Transfer of the methyl group from betaine to homocysteine creates methionine, which donates the methyl group to methylate DNA, proteins, lipids, and other intracellular metabolites. BHMT2 is one of two methyl transferases that can catalyze the transfer of the methyl group from betaine to homocysteine. Recombinant human BHMT2 protein, fused to His-tag at N-terminus, was expressed in E.coli.

Molecular Weight: 42.7 kDa (386aa)

NCBI Accession: NP_060084

UniProt: Q9H2M3

Pathways: Methionine Biosynthetic Process