XAF1 Protein (AA 1-125) (His tag)

Catalog No. ABIN5853700

Product Details

Target: XAF1 (XiAP Associated Factor 1 (XAF1))

Protein Type: Recombinant

Protein Characteristics: AA 1-125

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This XAF1 protein is labelled with His tag.

Application: SDS-PAGE (SDS)

Sequence: MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSMEGD FSVCRNCKRH VVSANFTLHE AYCLRFLVLC PECEEPVPKE TMEEHCKLEH QQVGCTMCQQ SMQKSSLEFH KANECQERPV ECKFCKLDMQ LSKLELHESY CGSRTELCQG CGQFIMHRML A

Purity: > 90 % by SDS - PAGE

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. In 20  mM Tris-HCl buffer (  pH 8.0) containing 30 % glycerol 0.15M NaCl, 1  mM DTT

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.

Target Details

Target: XAF1 (XiAP Associated Factor 1 (XAF1))

Alternative Name: XAF1 (XAF1 Products)

Synonyms: BIRC4BP Protein, HSXIAPAF1 Protein, XIAPAF1 Protein, Fbxo39 Protein, XIAP associated factor 1 Protein, xaf1 Protein, XAF1 Protein, Xaf1 Protein

Background: XAF1 is a protein which binds to and counteracts the inhibitory effect of a member of the IAP (inhibitor of apoptosis) protein family. IAP proteins bind to and inhibit caspases which are activated during apoptosis. The proportion of IAPs and proteins which interfere with their activity, such as the encoded protein, affect the progress of the apoptosis signaling pathway. Multiple transcript variants encoding different isoforms have been found for this gene. Recombinant human XAF1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Molecular Weight: .6 kDa (161aa) confirmed by MALDI-TOF

NCBI Accession: NP_059993

UniProt: Q6GPH4